UTP20

Across TCGA cell cohorts, UTP20 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,647 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UTP20-associated GO terms across cancer lineages are Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA), and Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with UTP20 in more than 19 cancer types. Because this analysis shows association rather than direction, both UTP20-to-partner and partner-to-UTP20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by UTP20-low versus UTP20-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP20→partner) and Y-score (partner→UTP20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.144	+1.171	<.001	<.001	3	20
LIVER	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.189	+1.209	<.001	<.001	3	20
BONE	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.163	+1.024	<.001	.001	3	20
BONE	Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.171	+1.029	.001	.001	3	20
LIVER	rRNA 5'-end processing →	+0.189	+1.209	<.001	<.001	3	20
BONE	Maturation of 5.8S rRNA →	+0.158	+1.040	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,647 associations by consensus.

Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by UTP20 expression — BONE

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