UTP20

Across TCGA cell cohorts, UTP20 mutation is significantly associated with the RNA expression of many other genes, with 2,232 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UTP20-associated genes across cancer lineages are SDE2, C17orf98, and BAG2. Each is linked with UTP20 in more than 2 cancer types. Because this analysis shows association rather than direction, both UTP20-to-partner and partner-to-UTP20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SDE2 grouped by UTP20-low versus UTP20-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP20→partner) and Y-score (partner→UTP20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SDE2 →	+0.629	+3.489	.007	.001	3	3
UPPER_AERODIGESTIVE_TRACT	C17orf98 →	+0.061	+3.129	<.001	.007	3	3
LARGE_INTESTINE	BAG2 →	+0.848	+2.584	.002	.002	3	3
LARGE_INTESTINE	AEBP2 →	+0.409	+2.459	.002	.006	3	3
LARGE_INTESTINE	ZNF131 →	+0.506	+3.409	<.001	<.001	3	3
BLOOD_Myeloma	MMP26 →	+0.026	+4.807	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,232 associations by consensus.

SDE2 by UTP20 expression — BLOOD_Leukemia

Explore this box plot interactively →