UTP14C

Across TCGA cell cohorts, UTP14C mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UTP14C-associated genes across cancer lineages are OR56A5, IQCF3, and OR8B4. Each is linked with UTP14C in more than 1 cancer types. Because this analysis shows association rather than direction, both UTP14C-to-partner and partner-to-UTP14C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR56A5 grouped by UTP14C-low versus UTP14C-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP14C→partner) and Y-score (partner→UTP14C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR56A5 →	+0.111	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	IQCF3 →	+0.045	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR8B4 →	+0.045	+4.887	<.001	.009	3	1
SKIN	KRTAP5-10 →	+0.028	+2.657	<.001	.007	3	1
BLOOD_Leukemia	LCE1C →	+0.432	+4.922	.002	.009	3	1
BLOOD_Leukemia	SLC5A8 →	+0.182	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

OR56A5 by UTP14C expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →