Across TCGA patient cohorts, UTP11 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UTP11-associated genes across cancer lineages are N-Cadherin, Notch1, and PDCD4. Each is linked with UTP11 in more than 1 cancer types. Because this analysis shows association rather than direction, both UTP11-to-partner and partner-to-UTP11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UTP11→partner) and Y-score (partner→UTP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	N-Cadherin →	-0.258	-2.990	.008	.036	3	1
UCEC	Notch1 →	+0.237	+2.335	<.001	.018	3	1
UCEC	PDCD4 →	-0.638	-3.169	.003	.018	3	1
UCEC	Rad50 →	-0.273	-2.584	.015	.011	3	1
UCEC	PR →	-0.254	-3.000	.030	.036	2	1
UCEC	Caspase-8 →	-0.232	-3.321	.048	.010	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

UTP11 survival (RNA) · tumor vs normal (RNA) · all UTP11 data types