UTF1

Across TCGA patient cohorts, UTF1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. COAD shows the largest number of these associations.

The most reproducible UTF1-associated genes across cancer lineages are OR4C46 and RNA5SP409. Each is linked with UTF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UTF1-to-partner and partner-to-UTF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4C46 grouped by UTF1-low versus UTF1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UTF1→partner) and Y-score (partner→UTF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OR4C46 →	+0.179	+7.741	<.001	.009	3	1
COAD	RNA5SP409 →	+0.345	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR4C46 by UTF1 expression — COAD

Explore this box plot interactively →