Across TCGA pan-cancer cohorts, UST-AS1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of UST-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where UST-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types UST-AS1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

THCA and STAD are the cancer types where UST-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UST-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.096	.005	4	view →
STAD	Male	IV	+0.084	.003	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: UST-AS1 RNA expression & survival · all UST-AS1 data types