USP9YP35

Across TCGA patient cohorts, USP9YP35 RNA expression is significantly associated with the mutation status of many other genes, with 21 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible USP9YP35-associated genes across cancer lineages are GTF2H3, PERP, and COLEC11. Each is linked with USP9YP35 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP9YP35-to-partner and partner-to-USP9YP35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GTF2H3 grouped by USP9YP35-low versus USP9YP35-high in BRCA.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP9YP35→partner) and Y-score (partner→USP9YP35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GTF2H3 →	+7.473	+0.049	.007	<.001	3	1
BRCA	PERP →	+9.057	+0.099	.003	<.001	3	1
BRCA	COLEC11 →	+9.057	+0.099	.003	<.001	3	1
BRCA	ACTRT1 →	+7.057	+0.039	.009	<.001	3	1
BRCA	CCDC93 →	+8.057	+0.036	.005	<.001	3	1
BRCA	AP3B1 →	+7.473	+0.049	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

GTF2H3 by USP9YP35 expression — BRCA

Explore this box plot interactively →