USP9X

Across TCGA patient cohorts, USP9X RNA expression is significantly associated with the protein abundance of many other proteins, with 7,405 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible USP9X-associated proteins across cancer lineages are DDX3X, SYAP1, and UBA1. Each is linked with USP9X in more than 7 cancer types. Because this analysis shows association rather than direction, both USP9X-to-partner and partner-to-USP9X results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP9X versus DDX3X in GBM, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (USP9X→partner) and Y-score (partner→USP9X) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DDX3X →	+0.296	+0.313	<.001	<.001	3	8
UCEC	SYAP1 →	+0.493	+0.415	<.001	.001	3	4
BRCA	UBA1 →	+0.194	+0.489	.007	.005	2	5
CCRCC	NCBP1_S22 →	+0.428	+0.252	.008	.004	3	3
LSCC	OCRL →	+0.189	+0.353	<.001	<.001	3	3
LSCC	UFM1 →	-0.317	-0.430	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,405 associations by consensus.

USP9X vs DDX3X — GBM

Explore this scatter interactively →