USP9X

Across TCGA cell cohorts, USP9X RNA expression is significantly associated with the go_rna of many other GO terms, with 4,405 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible USP9X-associated GO terms across cancer lineages are Post-Golgi vesicle-mediated transport, Monoubiquitinated protein deubiquitination, and Cytosolic transport. Each is linked with USP9X in more than 18 cancer types. Because this analysis shows association rather than direction, both USP9X-to-partner and partner-to-USP9X results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Post-Golgi vesicle-mediated transport grouped by USP9X-low versus USP9X-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USP9X→partner) and Y-score (partner→USP9X) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Post-Golgi vesicle-mediated transport →	+0.072	+1.104	.002	<.001	3	19
LARGE_INTESTINE	Monoubiquitinated protein deubiquitination →	+0.125	+0.952	<.001	<.001	3	18
BONE	Cytosolic transport →	+0.069	+1.084	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.070	+1.326	.001	<.001	3	17
URINARY_TRACT	Growth hormone secretion →	+0.189	+0.919	<.001	<.001	3	16
BONE	Vesicle-mediated transport to the plasma membrane →	+0.071	+1.008	.008	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,405 associations by consensus.

Post-Golgi vesicle-mediated transport by USP9X expression — LUNG_NSCLC_LUSC

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