USP8

Across TCGA cell cohorts, USP8 RNA expression is significantly associated with the RNA expression of many other genes, with 11,240 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible USP8-associated genes across cancer lineages are DPP8, AP4E1, and TRPM7. Each is linked with USP8 in more than 18 cancer types. Because this analysis shows association rather than direction, both USP8-to-partner and partner-to-USP8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP8 versus DPP8 in OESOPHAGUS, with a Pearson correlation of 0.77.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP8→partner) and Y-score (partner→USP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	DPP8 →	+1.157	+1.027	<.001	<.001	3	19
LUNG_NSCLC_LUSC	AP4E1 →	+1.227	+0.798	<.001	<.001	3	19
STOMACH	TRPM7 →	+1.239	+1.026	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	SECISBP2L →	+1.241	+1.106	<.001	<.001	3	18
BREAST	BNIP2 →	+0.876	+0.795	<.001	.009	2	19
UPPER_AERODIGESTIVE_TRACT	COPS2 →	+0.901	+0.788	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,240 associations by consensus.

USP8 vs DPP8 — OESOPHAGUS

Explore this scatter interactively →