USP6NL

Across TCGA patient cohorts, USP6NL mutation is significantly associated with the RNA expression of many other genes, with 4,836 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible USP6NL-associated genes across cancer lineages are RNA5SP405, IGHD6-6, and RNU6-1213P. Each is linked with USP6NL in more than 2 cancer types. Because this analysis shows association rather than direction, both USP6NL-to-partner and partner-to-USP6NL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP405 grouped by USP6NL-low versus USP6NL-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP6NL→partner) and Y-score (partner→USP6NL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNA5SP405 →	+0.368	+3.505	<.001	.008	3	3
LGG	IGHD6-6 →	+0.970	+7.977	<.001	.007	3	3
UCEC	RNU6-1213P →	+0.137	+2.923	<.001	.001	3	3
CESC	RNA5SP325 →	+0.125	+4.252	<.001	.006	3	3
COAD	RNU6-738P →	+0.633	+4.927	<.001	.002	3	3
UCEC	ZFP91P1 →	+0.102	+1.847	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,836 associations by consensus.

RNA5SP405 by USP6NL expression — STAD

Explore this box plot interactively →