USP6NL

Across TCGA cell cohorts, USP6NL mutation is significantly associated with the RNA expression of many other genes, with 1,046 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible USP6NL-associated genes across cancer lineages are CTDNEP1, ALKBH5, and SULT1C3. Each is linked with USP6NL in more than 1 cancer types. Because this analysis shows association rather than direction, both USP6NL-to-partner and partner-to-USP6NL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CTDNEP1 grouped by USP6NL-low versus USP6NL-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP6NL→partner) and Y-score (partner→USP6NL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CTDNEP1 →	+0.560	+3.628	<.001	<.001	3	2
LARGE_INTESTINE	ALKBH5 →	+0.567	+2.502	.004	.005	3	2
BLOOD_Lymphoma	SULT1C3 →	+0.020	+6.247	<.001	<.001	3	2
OVARY	C20orf173 →	+0.031	+4.029	<.001	.009	3	2
BONE	OR1N2 →	+0.026	+5.169	<.001	.004	3	1
LARGE_INTESTINE	CBY1 →	+0.871	+3.714	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,046 associations by consensus.

CTDNEP1 by USP6NL expression — LARGE_INTESTINE

Explore this box plot interactively →