USP6

Across TCGA patient cohorts, USP6 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,916 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible USP6-associated proteins across cancer lineages are GLOD4, SP4_S46, and SULT2B1_S318. Each is linked with USP6 in more than 3 cancer types. Because this analysis shows association rather than direction, both USP6-to-partner and partner-to-USP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP6 versus GLOD4 in HNSC, with a Pearson correlation of 0.24.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (USP6→partner) and Y-score (partner→USP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GLOD4 →	+0.267	+0.432	<.001	.005	3	4
OV	SP4_S46 →	+0.636	+0.450	.003	.005	3	3
BRCA	SULT2B1_S318 →	-0.829	-0.303	.006	.009	3	3
BRCA	PYGO1_S34 →	+0.605	+0.352	.003	.001	3	3
HNSC	TLN2 →	+0.287	+0.404	.002	.001	3	3
LUAD	PRKD1_S249 →	+0.587	+0.277	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,916 associations by consensus.

USP6 vs GLOD4 — HNSC

Explore this scatter interactively →