USP6

Across TCGA patient cohorts, USP6 protein abundance is significantly associated with the RNA expression of many other genes, with 10,984 significant associations in total. GBM shows the largest number of these associations.

The most reproducible USP6-associated genes across cancer lineages are TTC12, LINC00928, and TMEM170B. Each is linked with USP6 in more than 5 cancer types. Because this analysis shows association rather than direction, both USP6-to-partner and partner-to-USP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP6 versus TTC12 in UCEC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP6→partner) and Y-score (partner→USP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TTC12 →	+0.961	+0.474	<.001	<.001	3	6
GBM	LINC00928 →	-1.000	-0.440	<.001	<.001	3	4
GBM	TMEM170B →	-0.846	-0.380	<.001	<.001	3	3
OV	ORC6 →	-1.251	-0.764	.001	.001	3	3
UCEC	CBL →	-0.391	-0.429	<.001	<.001	3	3
GBM	PARP11 →	-0.524	-0.364	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,984 associations by consensus.

USP6 vs TTC12 — UCEC

Explore this scatter interactively →