USP51

Across TCGA patient cohorts, USP51 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,643 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible USP51-associated proteins across cancer lineages are DDX21, EPM2AIP1, and HDGFL3. Each is linked with USP51 in more than 6 cancer types. Because this analysis shows association rather than direction, both USP51-to-partner and partner-to-USP51 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP51 versus DDX21 in BRCA, with a Pearson correlation of -0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (USP51→partner) and Y-score (partner→USP51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DDX21 →	-0.427	-0.351	<.001	<.001	3	6
OV	EPM2AIP1 →	+0.364	+0.795	<.001	.001	2	7
BRCA	HDGFL3 →	+0.551	+0.490	.007	.002	3	6
OV	TCEAL4 →	+0.441	+0.758	.002	.002	2	7
GBM	RPL3 →	-0.307	-0.541	.004	.004	3	5
LSCC	S100A12 →	-1.197	-0.502	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,643 associations by consensus.

USP51 vs DDX21 — BRCA

Explore this scatter interactively →