USP51

Across TCGA patient cohorts, USP51 protein abundance is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. GBM shows the largest number of these associations.

The most reproducible USP51-associated genes across cancer lineages are KCNIP2, POF1B, and PNCK. Each is linked with USP51 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP51-to-partner and partner-to-USP51 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP51 versus KCNIP2 in GBM, with a Pearson correlation of -0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP51→partner) and Y-score (partner→USP51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KCNIP2 →	-1.660	-0.549	.001	.009	3	1
GBM	POF1B →	-0.636	-0.549	.008	.009	3	1
GBM	PNCK →	-1.749	-0.549	.004	.009	3	1
GBM	PDE6B →	-1.053	-0.549	<.001	.009	3	1
GBM	AGAP2 →	-1.469	-0.549	.006	.009	3	1
GBM	NEK1 →	-0.949	-0.549	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

USP51 vs KCNIP2 — GBM

Explore this scatter interactively →