USP51

Across TCGA cell cohorts, USP51 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,513 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible USP51-associated GO terms across cancer lineages are Mitotic cytokinesis, Endoplasmic reticulum to Golgi vesicle-mediated transport, and Negative regulation of mitotic cell cycle phase transition. Each is linked with USP51 in more than 11 cancer types. Because this analysis shows association rather than direction, both USP51-to-partner and partner-to-USP51 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic cytokinesis grouped by USP51-low versus USP51-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USP51→partner) and Y-score (partner→USP51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Mitotic cytokinesis →	+0.067	+0.970	.001	.001	3	12
OESOPHAGUS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.081	+0.404	.002	<.001	3	12
LUNG_SCLC	Negative regulation of mitotic cell cycle phase transition →	+0.067	+1.358	<.001	<.001	3	11
BREAST	Regulation of stem cell population maintenance →	+0.079	+0.438	<.001	<.001	3	11
BLOOD_Lymphoma	Protein localization to chromosome →	+0.083	+0.520	<.001	<.001	3	11
OESOPHAGUS	Positive regulation of mitotic cell cycle →	+0.101	+0.565	.009	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,513 associations by consensus.

Mitotic cytokinesis by USP51 expression — LUNG_SCLC

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