USP51

Across TCGA cell cohorts, USP51 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible USP51-associated genes across cancer lineages are SCYGR2 and FAM205A. Each is linked with USP51 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP51-to-partner and partner-to-USP51 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCYGR2 grouped by USP51-low versus USP51-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP51→partner) and Y-score (partner→USP51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SCYGR2 →	+0.116	+5.285	<.001	.003	3	1
LARGE_INTESTINE	FAM205A →	+0.022	+4.614	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SCYGR2 by USP51 expression — STOMACH

Explore this box plot interactively →