USP48

Across TCGA patient cohorts, USP48 protein abundance is significantly associated with the RNA expression of many other genes, with 17,721 significant associations in total. GBM shows the largest number of these associations.

The most reproducible USP48-associated genes across cancer lineages are AUNIP, LZIC, and LMNB1. Each is linked with USP48 in more than 7 cancer types. Because this analysis shows association rather than direction, both USP48-to-partner and partner-to-USP48 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP48 versus AUNIP in UCEC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP48→partner) and Y-score (partner→USP48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AUNIP →	+0.768	+0.192	<.001	<.001	3	8
OV	LZIC →	+0.475	+0.356	<.001	<.001	3	8
GBM	LMNB1 →	+1.123	+0.349	<.001	<.001	3	7
GBM	NCAPH →	+1.000	+0.377	<.001	<.001	3	7
BRCA	STIL →	+0.814	+0.256	<.001	.002	3	7
GBM	BUB1 →	+1.043	+0.352	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,721 associations by consensus.

USP48 vs AUNIP — UCEC

Explore this scatter interactively →