USP46-DT

Across TCGA patient cohorts, USP46-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 12,538 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible USP46-DT-associated proteins across cancer lineages are RBM28, RPS8, and CASP4. Each is linked with USP46-DT in more than 3 cancer types. Because this analysis shows association rather than direction, both USP46-DT-to-partner and partner-to-USP46-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP46-DT versus RBM28 in BRCA, with a Pearson correlation of -0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (USP46-DT→partner) and Y-score (partner→USP46-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RBM28 →	-0.649	-0.817	<.001	<.001	3	4
GBM	RPS8 →	-0.297	-0.460	<.001	<.001	3	4
HNSC	CASP4 →	-0.481	-0.477	<.001	.002	3	4
BRCA	UBASH3B →	-0.574	-0.623	<.001	<.001	3	4
BRCA	CALR →	-0.399	-0.723	<.001	<.001	3	4
GBM	CAMP →	-1.088	-0.493	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,538 associations by consensus.

USP46-DT vs RBM28 — BRCA

Explore this scatter interactively →