USP45

Across TCGA patient cohorts, USP45 protein abundance is significantly associated with the RNA expression of many other genes, with 1,011 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible USP45-associated genes across cancer lineages are LINC01184, NEUROG3, and TMSB4Y. Each is linked with USP45 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP45-to-partner and partner-to-USP45 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP45 versus LINC01184 in BRCA, with a Pearson correlation of -0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP45→partner) and Y-score (partner→USP45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LINC01184 →	-0.807	-0.758	.003	.005	3	2
LSCC	NEUROG3 →	+0.051	+0.409	.002	.002	3	1
LSCC	TMSB4Y →	-0.600	-0.386	.003	.006	3	1
LSCC	PXYLP1 →	+0.772	+0.283	.001	.007	3	1
LSCC	TEPP →	+0.612	+0.491	<.001	<.001	3	1
LSCC	C1orf116 →	-0.712	-0.358	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,011 associations by consensus.

USP45 vs LINC01184 — BRCA

Explore this scatter interactively →