USP44

Across TCGA pan-cancer cohorts, USP44 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated USP44 data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher USP44 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated USP44 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

GBM and LUAD are the cancer types where USP44 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Tertile	All	0.209	0.967	.024	6	view →
LUAD	DFS	Quartile	All	0.977	0.771	.037	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

USP44–GBM (OS)

Open the GBM breakdown →