USP43

Across TCGA patient cohorts, USP43 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,722 significant associations in total. GBM shows the largest number of these associations.

The most reproducible USP43-associated proteins across cancer lineages are USP43_S818, USP43_S766, and TRAF4. Each is linked with USP43 in more than 7 cancer types. Because this analysis shows association rather than direction, both USP43-to-partner and partner-to-USP43 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP43 versus USP43_S818 in GBM, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (USP43→partner) and Y-score (partner→USP43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	USP43_S818 →	+1.585	+2.566	<.001	.008	3	8
UCEC	USP43_S766 →	+1.987	+1.412	.002	<.001	3	4
PDAC	TRAF4 →	+0.391	+0.404	<.001	<.001	3	4
LSCC	TSR1 →	+0.260	+0.772	.003	<.001	3	4
OV	KIF1C →	+0.313	+0.989	<.001	<.001	3	4
LUAD	RBM47 →	+0.248	+0.563	.007	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,722 associations by consensus.

USP43 vs USP43_S818 — GBM

Explore this scatter interactively →