USP42

Across TCGA patient cohorts, USP42 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,009 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible USP42-associated proteins across cancer lineages are FOXK1, CTNNBL1, and XPO1. Each is linked with USP42 in more than 6 cancer types. Because this analysis shows association rather than direction, both USP42-to-partner and partner-to-USP42 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP42 versus FOXK1 in LSCC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (USP42→partner) and Y-score (partner→USP42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FOXK1 →	+0.299	+0.384	<.001	<.001	3	7
LSCC	CTNNBL1 →	+0.231	+0.424	.002	.001	3	6
LSCC	XPO1 →	+0.224	+0.383	<.001	<.001	3	5
LSCC	SSRP1 →	+0.401	+0.417	<.001	.002	3	5
GBM	SUPT16H →	+0.395	+0.348	.003	.002	3	5
LSCC	ZNF316_S112 →	+0.389	+0.577	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,009 associations by consensus.

USP42 vs FOXK1 — LSCC

Explore this scatter interactively →