USP41

Across TCGA patient cohorts, USP41 protein abundance is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible USP41-associated genes across cancer lineages are RPS27AP18, KRT33A, and C16orf90. Each is linked with USP41 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP41-to-partner and partner-to-USP41 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP41 versus RPS27AP18 in BRCA, with a Pearson correlation of 0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP41→partner) and Y-score (partner→USP41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPS27AP18 →	+0.400	+3.026	<.001	.003	3	1
BRCA	KRT33A →	+0.295	+3.026	<.001	.003	3	1
BRCA	C16orf90 →	+0.500	+2.952	.003	.005	1	1
BRCA	HIGD2AP1 →	+0.540	+2.936	<.001	.001	1	1
BRCA	HMGN2P20 →	+0.620	+2.936	<.001	.001	1	1
BRCA	SLC25A48-AS1 →	+0.095	+2.936	.002	.001	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

USP41 vs RPS27AP18 — BRCA

Explore this scatter interactively →