USP32

Across TCGA cell cohorts, USP32 mutation is significantly associated with the RNA expression of many other genes, with 316 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible USP32-associated genes across cancer lineages are DPPA5, OR12D2, and DYNAP. Each is linked with USP32 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP32-to-partner and partner-to-USP32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DPPA5 grouped by USP32-low versus USP32-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP32→partner) and Y-score (partner→USP32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	DPPA5 →	+0.042	+2.959	<.001	.004	3	2
LUNG_NSCLC_LUAD	OR12D2 →	+0.065	+3.928	<.001	<.001	3	2
LUNG_SCLC	DYNAP →	+0.156	+2.392	<.001	.008	3	2
LARGE_INTESTINE	HMGXB4 →	+0.545	+3.169	.003	.005	3	2
BONE	SULT6B1 →	+0.023	+5.169	<.001	.004	3	1
OESOPHAGUS	ACTRT1 →	+0.023	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 316 associations by consensus.

DPPA5 by USP32 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →