USP26

Across TCGA patient cohorts, USP26 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,350 significant associations in total. STAD shows the largest number of these associations.

The most reproducible USP26-associated GO terms across cancer lineages are Transcription initiation at RNA polymerase II promoter, Telomere organization, and Positive regulation of cell division. Each is linked with USP26 in more than 12 cancer types. Because this analysis shows association rather than direction, both USP26-to-partner and partner-to-USP26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation at RNA polymerase II promoter grouped by USP26-low versus USP26-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USP26→partner) and Y-score (partner→USP26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Transcription initiation at RNA polymerase II promoter →	+0.062	+0.115	<.001	<.001	3	13
STAD	Telomere organization →	+0.058	+0.100	<.001	<.001	3	13
STAD	Positive regulation of cell division →	+0.044	+0.096	<.001	<.001	3	12
STAD	Vesicle targeting →	+0.061	+0.094	<.001	<.001	3	12
ESCA	Regulation of protein ubiquitination →	+0.073	+0.092	<.001	<.001	2	13
STAD	Regulation of microtubule-based process →	+0.047	+0.096	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,350 associations by consensus.

Transcription initiation at RNA polymerase II promoter by USP26 expression — STAD

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