USP24

Across TCGA cell cohorts, USP24 mutation is significantly associated with the RNA expression of many other genes, with 410 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible USP24-associated genes across cancer lineages are OR4X2, OR11H1, and OR9K2. Each is linked with USP24 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP24-to-partner and partner-to-USP24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4X2 grouped by USP24-low versus USP24-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP24→partner) and Y-score (partner→USP24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR4X2 →	+0.032	+5.369	<.001	.004	3	2
LUNG_NSCLC_LUAD	OR11H1 →	+0.012	+2.786	.004	.007	3	2
BLOOD_Lymphoma	OR9K2 →	+0.010	+3.925	<.001	.006	3	2
LARGE_INTESTINE	TRPS1 →	+0.965	+2.064	.001	.004	3	2
LARGE_INTESTINE	ZFP90 →	+0.566	+1.850	.004	.006	3	2
LARGE_INTESTINE	PRR27 →	+0.063	+1.732	.006	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 410 associations by consensus.

OR4X2 by USP24 expression — SOFT_TISSUE

Explore this box plot interactively →