USP24

Across TCGA pan-cancer cohorts, USP24 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated USP24 data layer compared with 8 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher USP24 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated USP24 expression acts as an unfavorable survival marker, although some lineages such as KIRC and UCS show a favorable association.

LIHC, KIRC, and UCS are the cancer types where USP24 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	All	0.552	0.752	<.001	101	view →
KIRC	OS	Quartile	All	0.756	0.557	<.001	86	view →
UCS	DFS	Median	IV	0.952	0.367	.001	84	view →
HNSC	DFS	Quartile	All	0.705	0.513	.002	72	view →
MESO	DFS	Tertile	All	0.262	0.504	.001	45	view →
KIRP	DFS	Quartile	All	0.784	0.942	.002	39	view →
LGG	OS	Tertile	All	0.736	0.879	<.001	36	view →
CESC	DFS	Quartile	All	0.457	0.772	.004	32	view →
SARC	OS	Tertile	All	0.380	0.665	<.001	30	view →
READ	DFS	Median	III,IV	0.676	0.372	.006	29	view →
GBM	OS	Tertile	All	0.688	0.282	<.001	28	view →
ACC	DFS	Quartile	II,III,IV	0.240	0.742	.008	28	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

USP24–LIHC (OS)

Open the LIHC breakdown →