USP19

Across TCGA patient cohorts, USP19 protein abundance is significantly associated with the RNA expression of many other genes, with 3,058 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible USP19-associated genes across cancer lineages are RFT1, ATRIP, and CCDC12. Each is linked with USP19 in more than 4 cancer types. Because this analysis shows association rather than direction, both USP19-to-partner and partner-to-USP19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP19 versus RFT1 in UCEC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP19→partner) and Y-score (partner→USP19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RFT1 →	+0.633	+0.146	.002	.002	3	5
LUAD	ATRIP →	+0.363	+0.140	<.001	<.001	3	4
LUAD	CCDC12 →	+0.221	+0.106	.002	.002	3	4
LUAD	PRKAR2A →	+0.287	+0.118	<.001	<.001	3	3
BRCA	UQCRC1 →	+0.584	+0.228	<.001	<.001	3	3
BRCA	RRP9 →	+0.708	+0.240	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,058 associations by consensus.

USP19 vs RFT1 — UCEC

Explore this scatter interactively →