USP19

Across TCGA cell cohorts, USP19 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,233 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible USP19-associated GO terms across cancer lineages are Nucleosome disassembly, P-body assembly, and Nuclear export. Each is linked with USP19 in more than 16 cancer types. Because this analysis shows association rather than direction, both USP19-to-partner and partner-to-USP19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleosome disassembly grouped by USP19-low versus USP19-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USP19→partner) and Y-score (partner→USP19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Nucleosome disassembly →	+0.200	+1.100	<.001	<.001	3	17
BONE	P-body assembly →	+0.116	+0.795	.001	.001	3	17
BONE	Nuclear export →	+0.111	+0.865	.002	<.001	3	16
SOFT_TISSUE	Viral translational termination-reinitiation →	+0.099	+0.907	<.001	<.001	3	16
BONE	RNA export from nucleus →	+0.126	+0.755	<.001	<.001	3	15
SKIN	Regulation of autophagosome maturation →	+0.088	+1.133	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,233 associations by consensus.

Nucleosome disassembly by USP19 expression — KIDNEY

Explore this box plot interactively →