USP17L4

Across TCGA cell cohorts, USP17L4 RNA expression is significantly associated with the go_rna of many other GO terms, with 250 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible USP17L4-associated GO terms across cancer lineages are Cellular response to starvation, Response to starvation, and Nuclear transport. Each is linked with USP17L4 in more than 4 cancer types. Because this analysis shows association rather than direction, both USP17L4-to-partner and partner-to-USP17L4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to starvation grouped by USP17L4-low versus USP17L4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USP17L4→partner) and Y-score (partner→USP17L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cellular response to starvation →	+0.040	+0.061	.001	.002	3	5
UPPER_AERODIGESTIVE_TRACT	Response to starvation →	+0.042	+0.042	.001	.002	3	5
UPPER_AERODIGESTIVE_TRACT	Nuclear transport →	+0.058	+0.045	.001	.007	3	3
UPPER_AERODIGESTIVE_TRACT	Host-mediated perturbation of symbiont process →	+0.050	+0.042	.002	.002	3	3
UPPER_AERODIGESTIVE_TRACT	Regulation of translational initiation →	+0.066	+0.042	<.001	.002	3	3
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to endoplasmic reticulum →	+0.061	+0.037	.004	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 250 associations by consensus.

Cellular response to starvation by USP17L4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →