USP17L11

Across TCGA cell cohorts, USP17L11 RNA expression is significantly associated with the mutation status of many other genes, with 160 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible USP17L11-associated genes across cancer lineages are ADAMTS19, NOTCH2, and HEPACAM2. Each is linked with USP17L11 in more than 1 cancer types. Because this analysis shows association rather than direction, both USP17L11-to-partner and partner-to-USP17L11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADAMTS19 grouped by USP17L11-low versus USP17L11-high in SOFT_TISSUE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP17L11→partner) and Y-score (partner→USP17L11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	ADAMTS19 →	+3.865	+0.146	.006	<.001	3	2
LUNG_NSCLC_LUSC	NOTCH2 →	+4.643	+0.090	.008	<.001	3	2
LUNG_SCLC	HEPACAM2 →	+4.523	+0.026	.003	<.001	3	2
BLOOD_Leukemia	PDPR →	+3.099	+0.009	.001	<.001	3	2
BLOOD_Leukemia	UBA7 →	+3.684	+0.012	<.001	<.001	3	2
BLOOD_Leukemia	AHNAK2 →	+2.099	+0.005	.003	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 160 associations by consensus.

ADAMTS19 by USP17L11 expression — SOFT_TISSUE

Explore this box plot interactively →