USP17L1

Across TCGA patient cohorts, USP17L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,804 significant associations in total. THYM shows the largest number of these associations.

The most reproducible USP17L1-associated GO terms across cancer lineages are Protein poly-ADP-ribosylation, Appendage morphogenesis, and Negative regulation of organelle assembly. Each is linked with USP17L1 in more than 11 cancer types. Because this analysis shows association rather than direction, both USP17L1-to-partner and partner-to-USP17L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein poly-ADP-ribosylation grouped by USP17L1-low versus USP17L1-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USP17L1→partner) and Y-score (partner→USP17L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Protein poly-ADP-ribosylation →	+0.052	+0.028	<.001	<.001	3	12
THYM	Appendage morphogenesis →	+0.043	+0.046	<.001	.001	3	12
SARC	Negative regulation of organelle assembly →	+0.033	+0.017	<.001	<.001	3	11
THYM	Non-motile cilium assembly →	+0.046	+0.029	<.001	<.001	3	11
THYM	Lysosomal transport →	+0.034	+0.048	<.001	<.001	3	11
THYM	Axon guidance →	+0.040	+0.030	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,804 associations by consensus.

Protein poly-ADP-ribosylation by USP17L1 expression — THYM

Explore this box plot interactively →