USP17L1

Across TCGA cell cohorts, USP17L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 711 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible USP17L1-associated GO terms across cancer lineages are Mitochondrial electron transport, cytochrome c to oxygen, Retina layer formation, and Regulation of pattern recognition receptor signaling pathway. Each is linked with USP17L1 in more than 5 cancer types. Because this analysis shows association rather than direction, both USP17L1-to-partner and partner-to-USP17L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial electron transport, cytochrome c to oxygen grouped by USP17L1-low versus USP17L1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USP17L1→partner) and Y-score (partner→USP17L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Mitochondrial electron transport, cytochrome c to oxygen →	+0.056	+0.025	<.001	.006	3	6
SOFT_TISSUE	Retina layer formation →	-0.306	-0.053	.002	.001	3	4
SOFT_TISSUE	Regulation of pattern recognition receptor signaling pathway →	+0.029	+0.030	.001	.007	2	5
SOFT_TISSUE	Actin polymerization-dependent cell motility →	+0.129	+0.036	<.001	.005	2	5
SKIN	Regulation of protein modification by small protein conjugation or removal →	+0.028	+0.022	.009	.002	3	4
BLOOD_Leukemia	Electron transport chain →	+0.054	+0.018	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 711 associations by consensus.

Mitochondrial electron transport, cytochrome c to oxygen by USP17L1 expression — BLOOD_Leukemia

Explore this box plot interactively →