USP16

Across TCGA patient cohorts, USP16 protein abundance is significantly associated with the RNA expression of many other genes, with 7,470 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible USP16-associated genes across cancer lineages are CCT8, ATE1, and FST. Each is linked with USP16 in more than 6 cancer types. Because this analysis shows association rather than direction, both USP16-to-partner and partner-to-USP16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USP16 versus CCT8 in UCEC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USP16→partner) and Y-score (partner→USP16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCT8 →	+0.701	+0.207	<.001	<.001	2	7
GBM	ATE1 →	-0.419	-0.274	<.001	<.001	3	4
OV	FST →	-1.617	-0.304	<.001	<.001	3	4
UCEC	GART →	+0.526	+0.170	<.001	<.001	3	4
GBM	PLEKHA1 →	-0.513	-0.294	<.001	<.001	3	3
LSCC	SCAF4 →	+0.381	+0.100	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,470 associations by consensus.

USP16 vs CCT8 — UCEC

Explore this scatter interactively →