Across TCGA pan-cancer cohorts, USP12PX RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of USP12PX’s most consistent transcriptional readouts.
The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where USP12PX RNA is repressed in tumor relative to normal tissue. In most cancer types USP12PX is over-expressed in tumor, although a few such as PAAD and UCEC show the opposite, repressed pattern.
PAAD, UCEC, and READ are the cancer types where USP12PX tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in USP12PX RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.