Q-omics provides the consensus-scored USP12P1 profile across patient tissues and cancer cell-line models. USP12P1 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in STAD. Among the 18 cancer types available for tumor–normal comparison, USP12P1 is differentially expressed in 10, with the highest sampling consensus in LUSC. Additionally, USP12P1 RNA expression shows 16,641 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight STAD, LUSC, and UVM as cancer lineages where USP12P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for USP12P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes USP12P1 survival associations across molecular data types. USP12P1 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible USP12P1 RNA expression–survival associations across cancer types. High USP12P1 expression shows unfavorable associations in STAD, ESCA, UCEC and LUSC, but favorable associations in LGG and UCS. The STAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify STAD as the clearest survival context for USP12P1 RNA expression.
This table summarizes USP12P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for USP12P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. USP12P1 shows lower tumor expression in LUSC and THCA and higher tumor expression in BLCA, BRCA, KIRP and CHOL. The LUSC box plot shows higher USP12P1 RNA expression in normal versus tumor tissue (log2 FC = −0.145, t-test p = .006).
This table shows molecular features associated with USP12P1 in patient tissues and cancer cell lines. In patient samples, USP12P1 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
