USO1

Across TCGA cell cohorts, USO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,145 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible USO1-associated GO terms across cancer lineages are Transcytosis, Golgi organization, and Positive regulation of protein exit from endoplasmic reticulum. Each is linked with USO1 in more than 16 cancer types. Because this analysis shows association rather than direction, both USO1-to-partner and partner-to-USO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcytosis grouped by USO1-low versus USO1-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USO1→partner) and Y-score (partner→USO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Transcytosis →	+0.184	+0.552	<.001	<.001	2	17
BREAST	Golgi organization →	+0.046	+0.606	<.001	<.001	3	15
OESOPHAGUS	Positive regulation of protein exit from endoplasmic reticulum →	+0.143	+0.423	<.001	<.001	3	14
PANCREAS	Golgi vesicle transport →	+0.063	+0.707	<.001	<.001	3	13
OESOPHAGUS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.087	+0.492	.008	.003	3	13
OESOPHAGUS	Positive regulation of ER to Golgi vesicle-mediated transport →	+0.100	+0.563	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,145 associations by consensus.

Transcytosis by USO1 expression — CNS

Explore this box plot interactively →