USO1

Across TCGA cell cohorts, USO1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,530 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible USO1-associated genes across cancer lineages are PPP1CC, RPL3, and C1QBP. Each is linked with USO1 in more than 6 cancer types. Because this analysis shows association rather than direction, both USO1-to-partner and partner-to-USO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USO1 versus PPP1CC in BLOOD_Myeloma, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USO1→partner) and Y-score (partner→USO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	PPP1CC →	+0.457	+0.659	.004	.002	3	7
OVARY	RPL3 →	+0.937	+1.759	.006	.002	3	7
UPPER_AERODIGESTIVE_TRACT	C1QBP →	+1.431	+1.865	.001	<.001	3	7
STOMACH	EEF2 →	+1.237	+1.538	<.001	.005	3	7
STOMACH	GSN →	-2.769	-1.349	.001	<.001	3	7
PANCREAS	LSM12 →	+0.694	+1.943	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,530 associations by consensus.

USO1 vs PPP1CC — BLOOD_Myeloma

Explore this scatter interactively →