USH2A-AS2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, USH2A-AS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,859 significant associations in total. STAD shows the largest number of these associations.

The most reproducible USH2A-AS2-associated GO terms across cancer lineages are Vesicle localization, Protein localization to mitochondrion, and Intrinsic apoptotic signaling pathway by p53 class mediator. Each is linked with USH2A-AS2 in more than 4 cancer types. Because this analysis shows association rather than direction, both USH2A-AS2-to-partner and partner-to-USH2A-AS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle localization grouped by USH2A-AS2-low versus USH2A-AS2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (USH2A-AS2→partner) and Y-score (partner→USH2A-AS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADVesicle localization →+0.131+0.045<.001<.00135
STADProtein localization to mitochondrion →+0.151+0.043<.001<.00135
STADIntrinsic apoptotic signaling pathway by p53 class mediator →+0.141+0.040<.001<.00135
STADAerobic respiration →+0.182+0.047<.001<.00135
STADGlial cell differentiation →+0.100+0.046<.001<.00135
STADTelencephalon development →+0.091+0.045<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,859 associations by consensus.

Vesicle localization by USH2A-AS2 expression — STAD

Box plot of Vesicle localization in USH2A-AS2-low vs USH2A-AS2-high samples in STAD.

Explore this box plot interactively →

Exploration