USH2A-AS2

Across TCGA pan-cancer cohorts, USH2A-AS2 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated USH2A-AS2 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher USH2A-AS2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated USH2A-AS2 expression acts as an unfavorable survival marker, although some lineages such as ESCA and LUAD show a favorable association.

STAD, BLCA, and COAD are the cancer types where USH2A-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Tertile	All	0.471	0.677	<.001	63	view →
BLCA	DFS	Tertile	All	0.228	0.618	.003	54	view →
COAD	OS	Tertile	All	0.500	0.871	.025	27	view →
UCS	OS	Tertile	All	0.185	0.686	.034	18	view →
LUSC	DFS	Tertile	II,III,IV	0.185	0.717	.012	18	view →
LIHC	OS	Tertile	All	0.061	0.783	<.001	18	view →
PRAD	DFS	Tertile	All	0.628	0.936	.003	18	view →
LGG	DFS	Tertile	All	0.224	0.738	.013	18	view →
ESCA	OS	Tertile	III,IV	1.000	0.371	.030	12	view →
LUAD	OS	Tertile	III,IV	1.000	0.478	.024	12	view →
SKCM	DFS	Tertile	All	0.603	0.746	.034	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

USH2A-AS2–STAD (DFS)

Open the STAD breakdown →