USH1C

Across TCGA patient cohorts, USH1C RNA expression is significantly associated with the protein abundance of many other proteins, with 15,500 significant associations in total. GBM shows the largest number of these associations.

The most reproducible USH1C-associated proteins across cancer lineages are KIF21A_S1212, C12orf75, and EPS8L3. Each is linked with USH1C in more than 4 cancer types. Because this analysis shows association rather than direction, both USH1C-to-partner and partner-to-USH1C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USH1C versus KIF21A_S1212 in LUAD, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (USH1C→partner) and Y-score (partner→USH1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	KIF21A_S1212 →	+0.611	+1.288	<.001	<.001	3	5
LSCC	C12orf75 →	+0.539	+0.744	<.001	<.001	3	4
LUAD	EPS8L3 →	+2.238	+3.563	<.001	<.001	3	4
GBM	ABLIM1 →	+0.415	+1.023	<.001	<.001	3	4
GBM	PLEKHA6 →	+0.419	+1.209	<.001	<.001	3	4
GBM	PLEKHA6_S459 →	+0.969	+1.329	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,500 associations by consensus.

USH1C vs KIF21A_S1212 — LUAD

Explore this scatter interactively →