USH1C

Across TCGA patient cohorts, USH1C protein abundance is significantly associated with the RNA expression of many other genes, with 10,802 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible USH1C-associated genes across cancer lineages are RSPH14, CCN4, and MEIS3. Each is linked with USH1C in more than 2 cancer types. Because this analysis shows association rather than direction, both USH1C-to-partner and partner-to-USH1C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USH1C versus RSPH14 in CCRCC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (USH1C→partner) and Y-score (partner→USH1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RSPH14 →	+0.458	+0.418	<.001	<.001	3	3
COAD	CCN4 →	-1.021	-0.338	<.001	<.001	3	3
CCRCC	MEIS3 →	-0.621	-0.546	<.001	<.001	3	3
PDAC	CAV1 →	-1.211	-0.765	<.001	<.001	3	3
CCRCC	MOGAT3 →	+1.097	+0.367	<.001	<.001	3	3
COAD	CLEC2B →	-1.024	-0.473	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,802 associations by consensus.

USH1C vs RSPH14 — CCRCC

Explore this scatter interactively →