USE1

Across TCGA patient cohorts, USE1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,953 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible USE1-associated proteins across cancer lineages are AKAP8, BRD4, and HNRNPM. Each is linked with USE1 in more than 6 cancer types. Because this analysis shows association rather than direction, both USE1-to-partner and partner-to-USE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, USE1 versus AKAP8 in OV, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (USE1→partner) and Y-score (partner→USE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	AKAP8 →	+0.325	+0.596	<.001	<.001	3	7
OV	BRD4 →	+0.334	+0.468	<.001	<.001	3	6
GBM	HNRNPM →	+0.346	+0.500	<.001	<.001	3	5
GBM	KRI1 →	+0.348	+0.244	<.001	<.001	3	5
GBM	SUGP1 →	+0.330	+0.402	<.001	<.001	3	5
GBM	WIZ →	+0.407	+0.408	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,953 associations by consensus.

USE1 vs AKAP8 — OV

Explore this scatter interactively →