UROD

Across TCGA cell cohorts, UROD RNA expression is significantly associated with the go_rna of many other GO terms, with 4,825 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UROD-associated GO terms across cancer lineages are Transport of virus, Intracellular transport of virus, and Protein-RNA covalent cross-linking repair. Each is linked with UROD in more than 12 cancer types. Because this analysis shows association rather than direction, both UROD-to-partner and partner-to-UROD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transport of virus grouped by UROD-low versus UROD-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UROD→partner) and Y-score (partner→UROD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Transport of virus →	+0.171	+0.825	<.001	<.001	3	13
BREAST	Intracellular transport of virus →	+0.171	+0.825	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Protein-RNA covalent cross-linking repair →	+0.119	+1.214	<.001	.002	3	11
LUNG_SCLC	Establishment or maintenance of microtubule cytoskeleton polarity →	+0.175	+0.615	.003	.001	3	11
CNS	Establishment of epithelial cell apical/basal polarity →	+0.157	+0.811	<.001	<.001	3	11
STOMACH	Cardiac conduction →	-0.189	-0.968	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,825 associations by consensus.

Transport of virus by UROD expression — BREAST

Explore this box plot interactively →