URGCP-MRPS24

Across TCGA patient cohorts, URGCP-MRPS24 RNA expression is significantly associated with the mutation status of many other genes, with 6,643 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible URGCP-MRPS24-associated genes across cancer lineages are FLG, XIRP2, and ZNF407. Each is linked with URGCP-MRPS24 in more than 4 cancer types. Because this analysis shows association rather than direction, both URGCP-MRPS24-to-partner and partner-to-URGCP-MRPS24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FLG grouped by URGCP-MRPS24-low versus URGCP-MRPS24-high in READ.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (URGCP-MRPS24→partner) and Y-score (partner→URGCP-MRPS24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	FLG →	+2.584	+0.166	.007	<.001	3	5
HNSC	XIRP2 →	+1.585	+0.106	.003	<.001	3	4
LUAD	ZNF407 →	+2.747	+0.111	.003	.008	3	4
UCEC	SI →	+1.211	+0.123	<.001	<.001	3	4
HNSC	SVIL →	+2.735	+0.190	.004	<.001	3	3
LGG	EGFR →	+2.212	+0.237	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,643 associations by consensus.

FLG by URGCP-MRPS24 expression — READ

Explore this box plot interactively →