URGCP-MRPS24

Across TCGA pan-cancer cohorts, URGCP-MRPS24 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated URGCP-MRPS24 data layer compared with 1 for mutation status.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher URGCP-MRPS24 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated URGCP-MRPS24 expression acts as an unfavorable survival marker, although some lineages such as KIRP and KIRC show a favorable association.

KIRP, SCLC, and KIRC are the cancer types where URGCP-MRPS24 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	II,III,IV	0.842	0.157	<.001	48	view →
SCLC	OS	Median	III,IV	0.293	0.640	.001	43	view →
KIRC	DFS	Tertile	All	0.860	0.744	.002	37	view →
PAAD	DFS	Median	All	0.396	0.153	.001	35	view →
COAD	DFS	Tertile	II,III,IV	0.391	0.631	.002	33	view →
KICH	OS	Tertile	All	0.619	1.000	.005	19	view →
LUAD	DFS	Median	IV	0.214	0.775	.003	18	view →
LUSC	DFS	Quartile	All	0.489	0.324	.003	16	view →
CHOL	DFS	Tertile	All	0.696	0.149	.001	12	view →
UCEC	OS	Quartile	IV	0.397	0.790	.007	12	view →
CESC	OS	Median	All	0.688	0.476	.010	12	view →
UCS	OS	Median	IV	0.732	0.224	.018	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

URGCP-MRPS24–KIRP (DFS)

Open the KIRP breakdown →