UQCRHL

Across TCGA pan-cancer cohorts, UQCRHL RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated UQCRHL data layer compared with 1 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher UQCRHL RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated UQCRHL expression acts as an unfavorable survival marker, although some lineages such as STAD and LUSC show a favorable association.

ACC, KIRC, and LIHC are the cancer types where UQCRHL RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.245	0.646	<.001	67	view →
KIRC	DFS	Median	IV	0.479	0.743	<.001	64	view →
LIHC	OS	Median	All	0.693	0.862	<.001	61	view →
KICH	OS	Median	III,IV	0.468	1.000	.001	49	view →
THCA	OS	Tertile	All	0.793	1.000	.004	49	view →
ESCA	DFS	Median	IV	0.205	0.634	.006	36	view →
LUAD	DFS	Median	III,IV	0.464	0.780	<.001	29	view →
SARC	OS	Median	All	0.638	0.812	.003	27	view →
STAD	DFS	Median	All	0.610	0.457	.001	24	view →
PRAD	DFS	Median	All	0.638	0.912	<.001	22	view →
BLCA	DFS	Median	III,IV	0.214	0.347	.015	18	view →
LGG	DFS	Median	All	0.656	0.792	.005	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

UQCRHL–ACC (DFS)

Open the ACC breakdown →