UQCRFS1

Across TCGA pan-cancer cohorts, UQCRFS1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated UQCRFS1 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher UQCRFS1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated UQCRFS1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

PDAC, LUAD, and CCRCC are the cancer types where UQCRFS1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	All	0.590	0.366	.005	16	view →
LUAD	OS	Median	All	0.930	0.989	.012	14	view →
CCRCC	OS	Tertile	All	1.000	0.878	.008	9	view →
OV	DFS	Median	All	0.942	0.652	.011	8	view →
GBM	OS	Median	All	0.933	0.775	.026	4	view →
LSCC	DFS	Tertile	III,IV	1.000	0.543	.036	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

UQCRFS1–PDAC (OS)

Open the PDAC breakdown →